The France international, who was on Euro 2020 duty with his country earlier in the summer, is being prevented from forming part of the Blancos squad.
Real Madrid have revealed that star striker Karim Benzema has tested positive for Covid-19.
The Liga giants, who are now working under the guidance of Carlo Ancelotti, are in the process of piecing together their plans for 2021-22.
A France international forward will play no part in pre-season training for the foreseeable future as he must now take in a period of self-isolation.
When are Real Madrid next in action?
The Blancos, who surrendered a domestic crown to neighbours Atletico Madrid in 2020-21, are in the process of completing a pre-season friendly programme.
They are due to face Scottish champions Rangers at Ibrox on Sunday, before then tackling Ancelotti’s former employers at AC Milan on August 8.
The new La Liga season will start for Real with a trip to Alaves on August 14.
